Using Stem Cells to Model Diseases of the Outer Retina

Using Stem Cells to Model Diseases of the Outer Retina

Retinal degeneration arises from the loss of photoreceptors or retinal pigment epithelium (RPE). It is one of the leading causes of irreversible blindness worldwide with limited effective treatment options. Generation of induced pluripotent stem cell (IPSC)-derived retinal cells and tissues from ind...

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Bibliographic Details
Main Authors: Camille Yvon, Conor M. Ramsden, Amelia Lane, Michael B. Powner, Lyndon da Cruz, Peter J. Coffey, Amanda-Jayne F. Carr
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Disease models
Induced pluripotent stem cells
Retinitis pigmentosa
Age related macular degeneration
Leber congenital amaurosis
Inherited retinopathy
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037015000276

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http://www.sciencedirect.com/science/article/pii/S2001037015000276

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