Physical restraint mouse models to assess immune responses under stress with or without habituation
Summary: Physical confinement, or restraint, is a psychological stressor used in rodent studies. A single restraint episode elevates blood corticosterone levels, a hallmark of stress responses. Repeated restraint results in habituation (or desensitization), whereas chronic exposure to unpredictable...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-12-01
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Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S266616672100544X |