Physical restraint mouse models to assess immune responses under stress with or without habituation

Summary: Physical confinement, or restraint, is a psychological stressor used in rodent studies. A single restraint episode elevates blood corticosterone levels, a hallmark of stress responses. Repeated restraint results in habituation (or desensitization), whereas chronic exposure to unpredictable...

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Bibliographic Details
Main Authors: Jian Xiang Ding, Patrick T. Rudak, Wataru Inoue, S.M. Mansour Haeryfar
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S266616672100544X