Enzymatic activities and DNA substrate specificity of Mycobacterium tuberculosis DNA helicase XPB.

XPB, also known as ERCC3 and RAD25, is a 3' → 5' DNA repair helicase belonging to the superfamily 2 of helicases. XPB is an essential core subunit of the eukaryotic basal transcription factor complex TFIIH. It has two well-established functions: in the context of damaged DNA, XPB facilitat...

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Bibliographic Details
Main Authors: Seetha V Balasingham, Ephrem Debebe Zegeye, Håvard Homberset, Marie L Rossi, Jon K Laerdahl, Vilhelm A Bohr, Tone Tønjum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22615856/?tool=EBI