Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan <i>Entamoeba histolytica</i>

Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan <i>Entamoeba histolytica</i>

A newly described &#946;-carbonic anhydrase (CA, EC 4.2.1.1) from the pathogenic protozoan <i>Entamoeba histolytica</i>, EhiCA, was recently shown to possess a significant catalytic activity for the physiologic CO<sub>2</sub> hydration reaction (k<sub>cat</sub>...

Full description

Bibliographic Details
Main Authors: Silvia Bua, Susanna Haapanen, Marianne Kuuslahti, Seppo Parkkila, Claudiu T. Supuran
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
carbonic anhydrase
metalloenzymes
protozoan
<i>Entamoeba histolytica</i>
sulfonamides
sulfamates
inhibitor
Online Access:https://www.mdpi.com/1422-0067/19/12/3946

Internet

https://www.mdpi.com/1422-0067/19/12/3946

Similar Items