Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons

Abstract We investigated the influence of genetic variants on atherosclerosis using whole exome sequencing in cases and controls from the autopsy study “Pathobiological Determinants of Atherosclerosis in Youth (PDAY)”. We identified a PDAY case group with the highest total amounts of raised lesions...

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Bibliographic Details
Main Authors: James E. Hixson, Goo Jun, Lawrence C. Shimmin, Yizhi Wang, Guoqiang Yu, Chunhong Mao, Andrew S. Warren, Timothy D. Howard, Richard S. Vander Heide, Jennifer Van Eyk, Yue Wang, David M. Herrington
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04433-x