Worsening of cardiomyopathy using deflazacort in an animal model rescued by gene therapy.

Worsening of cardiomyopathy using deflazacort in an animal model rescued by gene therapy.

We have previously demonstrated that gene therapy can rescue the phenotype and extend lifespan in the delta-sarcoglycan deficient cardiomyopathic hamster. In patients with similar genetic defects, steroids have been largely used to slow down disease progression. Aim of our study was to evaluate the...

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Bibliographic Details
Main Authors: Ida Luisa Rotundo, Stefania Faraso, Elvira De Leonibus, Gerardo Nigro, Carmen Vitiello, Alessio Lancioni, Daniele Di Napoli, Sigismondo Castaldo, Vincenzo Russo, Fabio Russo, Giulio Piluso, Alberto Auricchio, Vincenzo Nigro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3170375?pdf=render

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http://europepmc.org/articles/PMC3170375?pdf=render

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