Proteomic Phosphosite Analysis Identified Crucial NPM-ALK-Mediated NIPA Serine and Threonine Residues

Anaplastic large-cell lymphoma (ALCL) is an aggressive non-Hodgkin lymphoma that shows in 60% of cases a translocation t(2;5)(p23;q35), which leads to the expression of the oncogenic kinase NPM-ALK. The nuclear interaction partner of ALK (NIPA) defines an E3-SCF ligase that contributes to the timing...

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Bibliographic Details
Main Authors: Anina Gengenbacher, Alina Müller-Rudorf, Teresa Poggio, Linda Gräßel, Veronica I. Dumit, Stefanie Kreutmair, Lena J. Lippert, Justus Duyster, Anna L. Illert
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/16/4060