Mining the Protein Data Bank to Differentiate Error from Structural Variation in Clustered Static Structures: An Examination of HIV Protease

Mining the Protein Data Bank to Differentiate Error from Structural Variation in Clustered Static Structures: An Examination of HIV Protease

The Protein Data Bank (PDB) contains over 71,000 structures. Extensively studied proteins have hundreds of submissions available, including mutations, different complexes, and space groups, allowing for application of data-mining algorithms to analyze an array of static structures and gain insight a...

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Bibliographic Details
Main Authors: Robert McKenna, Mavis Agbandje-McKenna, Miorel-Lucian Palii, Balasubramanian Venkatakrishnan
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Viruses
Subjects:
B-factor and spatial variation
data mining
HIV protease
structure superposition
Online Access:http://www.mdpi.com/1999-4915/4/3/348/

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http://www.mdpi.com/1999-4915/4/3/348/

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