Deletion in the Bardet–Biedl Syndrome Gene <i>TTC8</i> Results in a Syndromic Retinal Degeneration in Dogs

Deletion in the Bardet–Biedl Syndrome Gene <i>TTC8</i> Results in a Syndromic Retinal Degeneration in Dogs

In golden retriever dogs, a 1 bp deletion in the canine <i>TTC8</i> gene has been shown to cause progressive retinal atrophy (PRA), the canine equivalent of retinitis pigmentosa. In humans, <i>TTC8</i> is also implicated in Bardet–Biedl syndrome (BBS). To investigate if the a...

Full description

Bibliographic Details
Main Authors: Suvi Mäkeläinen, Minas Hellsand, Anna Darlene van der Heiden, Elina Andersson, Elina Thorsson, Bodil S. Holst, Jens Häggström, Ingrid Ljungvall, Cathryn Mellersh, Finn Hallböök, Göran Andersson, Björn Ekesten, Tomas F. Bergström
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
Bardet–Biedl syndrome (BBS)
primary cilia
ciliopathy
BBS8
progressive retinal atrophy (PRA)
retinitis pigmentosa
Online Access:https://www.mdpi.com/2073-4425/11/9/1090

Internet

https://www.mdpi.com/2073-4425/11/9/1090

Similar Items