PTPN3 suppresses the proliferation and correlates with favorable prognosis of perihilar cholangiocarcinoma by inhibiting AKT phosphorylation

Background: Perihilar cholangiocarcinoma (PHCCA) is the most common type of human cholangiocarcinoma with a very dismal prognosis. Tumor markers and target drugs of PHCCA are desperately needed. Protein phosphatase N3 (PTPN3) has dual roles in the progression of human cancers, but its expression and...

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Bibliographic Details
Main Authors: Rongqi Sun, Tianli Chen, Meng Li, Zengli Liu, Bo Qiu, Zhipeng Li, Yunfei Xu, Chang Pan, Zongli Zhang
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
AKT
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219352059