PTPN3 suppresses the proliferation and correlates with favorable prognosis of perihilar cholangiocarcinoma by inhibiting AKT phosphorylation
Background: Perihilar cholangiocarcinoma (PHCCA) is the most common type of human cholangiocarcinoma with a very dismal prognosis. Tumor markers and target drugs of PHCCA are desperately needed. Protein phosphatase N3 (PTPN3) has dual roles in the progression of human cancers, but its expression and...
Main Authors: | Rongqi Sun, Tianli Chen, Meng Li, Zengli Liu, Bo Qiu, Zhipeng Li, Yunfei Xu, Chang Pan, Zongli Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
|
Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332219352059 |
Similar Items
-
HMGA1-TRIP13 axis promotes stemness and epithelial mesenchymal transition of perihilar cholangiocarcinoma in a positive feedback loop dependent on c-Myc
by: Zhipeng Li, et al.
Published: (2021-03-01) -
Development and external validation of a nomogram for predicting the effect of tumor size on survival of patients with perihilar cholangiocarcinoma
by: Yaodong Zhang, et al.
Published: (2020-10-01) -
Exosomal Cripto-1 Serves as a Potential Biomarker for Perihilar Cholangiocarcinoma
by: Chunxiao Hu, et al.
Published: (2021-08-01) -
Percutaneous Radio-frequency Assisted Liver Partition with Portal vein embolization in Staged liver resection (PRALPPS) in patients with perihilar and intrahepatic cholangiocarcinoma: evaluation of short-term results
by: O. V. Melekhina, et al.
Published: (2019-04-01) -
Leakage and Stenosis of the Hepaticojejunostomy Following Surgery for Perihilar Cholangiocarcinoma
by: Jan Bednarsch, et al.
Published: (2020-05-01)