Coreceptor and cytokine concentrations may not explain differences in disease progression observed in HIV-1 clade A and D infected Ugandans.

The use of cellular coreceptors and modulation of cytokine concentrations by HIV to establish a productive infection is well documented. However, it is unknown whether the expression of these proteins affects the course of HIV clade A and D disease, reported to have different progression rates.We in...

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Bibliographic Details
Main Authors: Edward Wright, Susan Mugaba, Paul Grant, Rosalind Parkes-Ratanshi, Lieve Van der Paal, Heiner Grosskurth, Pontiano Kaleebu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3104992?pdf=render