Computational study of hippocampal-septal theta rhythm changes due to β-amyloid-altered ionic channels.

Electroencephagraphy (EEG) of many dementia patients has been characterized by an increase in low frequency field potential oscillations. One of the characteristics of early stage Alzheimer's disease (AD) is an increase in theta band power (4-7 Hz). However, the mechanism(s) underlying the chan...

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Bibliographic Details
Main Authors: Xin Zou, Damien Coyle, Kongfatt Wong-Lin, Liam Maguire
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3123375?pdf=render