Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells

To study the role of WNT/β-catenin signaling in pancreatic adenocarcinoma, human BxPC-3 cell lines deficient of the central canonical WNT signaling protein β-catenin were established by using zinc-finger nuclease mediated targeted genomic disruption of the β-catenin gene (CTNNB1). Comparison of the...

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Bibliographic Details
Main Authors: Petter Angell Olsen, Kaja Lund, Stefan Krauss
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Genomics Data
Subjects:
WNT
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596015000446