Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression

<p>Abstract</p> <p>Background</p> <p>Hepatitis C virus (HCV) encodes several proteins that interfere with the host cell antiviral response. Previously, the serine protease NS3/4A was shown to inhibit IFN-β gene expression by blocking dsRNA-activated retinoic acid-induci...

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Bibliographic Details
Main Authors: Hiscott John, Lin Rongtuan, Kotenko Sergei, Sillanpää Maarit, Kaukinen Pasi, Melén Krister, Julkunen Ilkka
Format: Article
Language:English
Published: BMC 2006-09-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/3/1/66