<em>Cyprinid herpesvirus 3</em> Evolves In Vitro through an Assemblage of Haplotypes that Alternatively Become Dominant or Under-Represented

<em>Cyprinid herpesvirus 3</em> Evolves In Vitro through an Assemblage of Haplotypes that Alternatively Become Dominant or Under-Represented

Viruses are able to evolve in vitro by mutations after serial passages in cell cultures, which can lead to either a loss, or an increase, of virulence. Cyprinid herpesvirus 3 (CyHV-3), a 295-kb double-stranded DNA virus, is the etiological agent of the koi herpesvirus disease (KHVD). To assess the i...

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Bibliographic Details
Main Authors: Sandro Klafack, Anna-Sophie Fiston-Lavier, Sven M. Bergmann, Saliha Hammoumi, Lars Schröder, Walter Fuchs, Angela Lusiastuti, Pei-Yu Lee, Sarahi Vega Heredia, Master student consortium, Anne-Sophie Gosselin-Grenet, Jean-Christophe Avarre
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Viruses
Subjects:
Cyprinid herpesvirus 3
cell culture passages
virus evolution
haplotype sequence
Online Access:https://www.mdpi.com/1999-4915/11/8/754

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https://www.mdpi.com/1999-4915/11/8/754

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