Plasma Markers of Inflammation Linked to Clinical Progression and Decline During Preclinical AD

Plasma Markers of Inflammation Linked to Clinical Progression and Decline During Preclinical AD

ObjectiveTo examine the prospective association between blood biomarkers of immune functioning (i.e., innate immune activation, adaptive immunity, and inflammation) and subsequent cognitive decline and clinical progression to mild cognitive impairment (MCI) in cognitively normal individuals.MethodsT...

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Bibliographic Details
Main Authors: Alden L. Gross, Keenan A. Walker, Abhay R. Moghekar, Corinne Pettigrew, Anja Soldan, Marilyn S. Albert, Jeremy D. Walston
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
preclinical AD
inflammation
cytokines
cognitive decline
biomarkers
TNFR1
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00229/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2019.00229/full

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