Resource competition promotes tumour expansion in experimentally evolved cancer

Abstract Background Tumour progression involves a series of phenotypic changes to cancer cells, each of which presents therapeutic targets. Here, using techniques adapted from microbial experimental evolution, we investigate the evolution of tumour spreading - a precursor for metastasis and tissue i...

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Bibliographic Details
Main Authors: Tiffany B. Taylor, Anastasia V. Wass, Louise J. Johnson, Phil Dash
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Evolutionary Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12862-017-1117-6