Resource competition promotes tumour expansion in experimentally evolved cancer
Abstract Background Tumour progression involves a series of phenotypic changes to cancer cells, each of which presents therapeutic targets. Here, using techniques adapted from microbial experimental evolution, we investigate the evolution of tumour spreading - a precursor for metastasis and tissue i...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-12-01
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Series: | BMC Evolutionary Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12862-017-1117-6 |