Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs

Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs

<p>Abstract</p> <p>Background</p> <p>Exosomes or secreted bi-lipid vesicles from human ESC-derived mesenchymal stem cells (hESC-MSCs) have been shown to reduce myocardial ischemia/reperfusion injury in animal models. However, as hESC-MSCs are not infinitely expansible,...

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Bibliographic Details
Main Authors: Choo Andre, Lai Ruenn, Tan Soon, Yin Yijun, Arslan Fatih, Chen Tian, Padmanabhan Jayanthi, Lee Chuen, de Kleijn Dominique PV, Lim Sai
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/47

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http://www.translational-medicine.com/content/9/1/47

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