Microglial activation is not equivalent to neuroinflammation in alcohol-induced neurodegeneration: The importance of microglia phenotype

Microglial activation is not equivalent to neuroinflammation in alcohol-induced neurodegeneration: The importance of microglia phenotype

Excessive alcohol intake, a defining characteristic of an alcohol use disorder (AUD), results in neurodegeneration in the hippocampus and entorhinal cortex that has been linked to a variety of cognitive deficits. Neuroinflammation is thought to be a factor in alcohol-induced neurodegeneration, and m...

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Bibliographic Details
Main Authors: S. Alex Marshall, Justin A. McClain, Matthew L. Kelso, Deann M. Hopkins, James R. Pauly, Kimberly Nixon
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Neurobiology of Disease
Subjects:
Alcoholism
Alternative activation
Blood brain barrier
Cytokine
Entorhinal cortex
Ethanol
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113000077

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http://www.sciencedirect.com/science/article/pii/S0969996113000077

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