Safety and Efficacy of Intravitreal Chemotherapy (Melphalan) to Treat Vitreous Seeds in Retinoblastoma

Safety and Efficacy of Intravitreal Chemotherapy (Melphalan) to Treat Vitreous Seeds in Retinoblastoma

Background: Active vitreous seeds in eyes with retinoblastoma (Rb) adversely affects the treatment outcome. This study aimed to investigate the safety and efficacy of intravitreal melphalan chemotherapy (IViC) as a treatment for recurrent and refractory vitreous seeds in patients with Rb.Methods: We...

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Bibliographic Details
Main Authors: Yacoub A. Yousef, Mays Al Jboor, Mona Mohammad, Mustafa Mehyar, Mario D. Toro, Rashed Nazzal, Qusai H. Alzureikat, Magdalena Rejdak, Mutasem Elfalah, Iyad Sultan, Robert Rejdak, Maysa Al-Hussaini, Ibrahim Al-Nawaiseh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
chemotherapy
melphalan
ocular toxicity
retinoblastoma
vitreous seeds
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.696787/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.696787/full

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