Melatonin Inhibits Osteoclastogenesis and Osteolytic Bone Metastasis: Implications for Osteoporosis

Melatonin Inhibits Osteoclastogenesis and Osteolytic Bone Metastasis: Implications for Osteoporosis

Osteoblasts and osteoclasts are major cellular components in the bone microenvironment and they play a key role in the bone turnover cycle. Many risk factors interfere with this cycle and contribute to bone-wasting diseases that progressively destroy bone and markedly reduce quality of life. Melaton...

Full description

Bibliographic Details
Main Authors: Iona J. MacDonald, Hsiao-Chi Tsai, An-Chen Chang, Chien-Chung Huang, Shun-Fa Yang, Chih-Hsin Tang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
bone mass protection
bone metastasis
immunomodulation
melatonin
osteoclastogenesis
Online Access:https://www.mdpi.com/1422-0067/22/17/9435

Internet

https://www.mdpi.com/1422-0067/22/17/9435

Similar Items