The influence of sex steroid hormones in the immunopathology of experimental pulmonary tuberculosis.

The relation between men and women suffering pulmonary tuberculosis is 7/3 in favor to males. Sex hormones could be a significant factor for this difference, considering that testosterone impairs macrophage activation and pro-inflammatory cytokines production, while estrogens are proinflammatory med...

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Bibliographic Details
Main Authors: Estela Isabel Bini, Dulce Mata Espinosa, Brenda Marquina Castillo, Jorge Barrios Payán, Darío Colucci, Alejandro Francisco Cruz, Zyanya Lucía Zatarain, Edgar Alfonseca, Marta Romano Pardo, Oscar Bottasso, Rogelio Hernández Pando
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3983091?pdf=render