Endoglin inhibition leads to intussusceptive angiogenesis via activation of factors related to COUP-TFII signaling pathway.

Angiogenesis is a highly coordinated, extremely complex process orchestrated by multiple signaling molecules and blood flow conditions. While sprouting mode of angiogenesis is very well investigated, the molecular mechanisms underlying intussusception, the second mode of angiogenesis, remain largely...

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Bibliographic Details
Main Authors: Ruslan Hlushchuk, Beata Styp-Rekowska, Jehona Dzambazi, Monika Wnuk, Uyen Huynh-Do, Andrew Makanya, Valentin Djonov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5578572?pdf=render