Molecular Profiling of Keratinocyte Skin Tumors Links <i>Staphylococcus aureus</i> Overabundance and Increased Human β-Defensin-2 Expression to Growth Promotion of Squamous Cell Carcinoma

Molecular Profiling of Keratinocyte Skin Tumors Links <i>Staphylococcus aureus</i> Overabundance and Increased Human β-Defensin-2 Expression to Growth Promotion of Squamous Cell Carcinoma

The skin microbiota plays a prominent role in health and disease; however, its contribution to skin tumorigenesis is not well understood. We comparatively assessed the microbial community compositions from excision specimens of the main human non-melanoma skin cancers, actinic keratosis (AK), squamo...

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Bibliographic Details
Main Authors: Nandhitha Madhusudhan, Manuela R. Pausan, Bettina Halwachs, Marija Durdević, Markus Windisch, Jan Kehrmann, VijayKumar Patra, Peter Wolf, Petra Boukamp, Christine Moissl-Eichinger, Lorenzo Cerroni, Jürgen C. Becker, Gregor Gorkiewicz
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
skin microbiota
actinic keratosis
squamous cell carcinoma
basal cell carcinoma
<i>staphylococcus aureus</i>
antimicrobial peptides
human β-defensin
Online Access:https://www.mdpi.com/2072-6694/12/3/541

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https://www.mdpi.com/2072-6694/12/3/541

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