The Need for Antiepileptic Drug Chronotherapy to Treat Selected Childhood Epilepsy Syndromes and Avert the Harmful Consequences of Drug Resistance

Antiepileptic drug (AED) chronotherapy involves the delivery of a greater AED dose at the time of greatest seizure susceptibility usually associated with predictable seizure peaks. Although research has proven AED chronotherapy, commonly known as differential dosing, to be safe, well tolerated, and...

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Bibliographic Details
Main Authors: Sheryl Manganaro, Tobias Loddenkemper, Alexander Rotenberg
Format: Article
Language:English
Published: SAGE Publishing 2017-02-01
Series:Journal of Central Nervous System Disease
Online Access:https://doi.org/10.1177/1179573516685883