Eukaryotic initiation factor 4A2 promotes experimental metastasis and oxaliplatin resistance in colorectal cancer

Eukaryotic initiation factor 4A2 promotes experimental metastasis and oxaliplatin resistance in colorectal cancer

Abstract Background Deregulation of protein translation control is a hallmark of cancers. Eukaryotic initiation factor 4A2 (EIF4A2) is required for mRNA binding to ribosome and plays an important role in translation initiation. However, little is known about its functions in colorectal cancer (CRC)....

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Bibliographic Details
Main Authors: Zhan-Hong Chen, Jing-Jing Qi, Qi-Nian Wu, Jia-Huan Lu, Ze-Xian Liu, Yun Wang, Pei-Shan Hu, Ting Li, Jin-Fei Lin, Xiang-Yuan Wu, Lei Miao, Zhao-Lei Zeng, Dan Xie, Huai-Qiang Ju, Rui-Hua Xu, Feng Wang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Colorectal cancer
Eukaryotic initiation factor 4A2 (EIF4A2)
PDX
Silvestrol
ZNF143
Online Access:http://link.springer.com/article/10.1186/s13046-019-1178-z

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http://link.springer.com/article/10.1186/s13046-019-1178-z

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