Genomic meta-analysis of the interplay between 3D chromatin organization and gene expression programs under basal and stress conditions

Abstract Background Our appreciation of the critical role of the genome’s 3D organization in gene regulation is steadily increasing. Recent 3C-based deep sequencing techniques elucidated a hierarchy of structures that underlie the spatial organization of the genome in the nucleus. At the top of this...

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Bibliographic Details
Main Authors: Idan Nurick, Ron Shamir, Ran Elkon
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-018-0220-2