Tetrahydrodipicolinate N-succinyltransferase and dihydrodipicolinate synthase from Pseudomonas aeruginosa: structure analysis and gene deletion.

Tetrahydrodipicolinate N-succinyltransferase and dihydrodipicolinate synthase from Pseudomonas aeruginosa: structure analysis and gene deletion.

The diaminopimelic acid pathway of lysine biosynthesis has been suggested to provide attractive targets for the development of novel antibacterial drugs. Here we report the characterization of two enzymes from this pathway in the human pathogen Pseudomonas aeruginosa, utilizing structural biology, b...

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Bibliographic Details
Main Authors: Robert Schnell, Wulf Oehlmann, Tatyana Sandalova, Yvonne Braun, Carmen Huck, Marko Maringer, Mahavir Singh, Gunter Schneider
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22359568/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22359568/?tool=EBI

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