CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation

CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation

Abstract Background The presence of foamy macrophages and microglia containing intracellular myelin remnants is a pathological hallmark of neurodegenerative disorders such as multiple sclerosis (MS). Despite the importance of myelin internalization in affecting both central nervous system repair and...

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Bibliographic Details
Main Authors: Elien Grajchen, Elien Wouters, Britt van de Haterd, Mansour Haidar, Kévin Hardonnière, Tess Dierckx, Jana Van Broeckhoven, Celine Erens, Sven Hendrix, Saadia Kerdine-Römer, Jerome J. A. Hendriks, Jeroen F. J. Bogie
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Neuroinflammation
Subjects:
Macrophages
Microglia
Myelin
CD36
Neuroinflammation
Fatty acid
Online Access:http://link.springer.com/article/10.1186/s12974-020-01899-x

Internet

http://link.springer.com/article/10.1186/s12974-020-01899-x

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