Immunization with L. sigmodontis microfilariae reduces peripheral microfilaraemia after challenge infection by inhibition of filarial embryogenesis.

BACKGROUND:Lymphatic filariasis and onchocerciasis are two chronic diseases mediated by parasitic filarial worms causing long term disability and massive socioeconomic problems. Filariae are transmitted by blood-feeding mosquitoes that take up the first stage larvae from an infected host and deliver...

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Bibliographic Details
Main Authors: Sebastian Ziewer, Marc P Hübner, Bettina Dubben, Wolfgang H Hoffmann, Odile Bain, Coralie Martin, Achim Hoerauf, Sabine Specht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22413031/?tool=EBI