2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length
Ceramide is unusually abundant in epidermal stratum corneum and is important for permeability barrier function. Ceramides in epidermis also comprise an unusual variety, including 2-hydroxy (α-hydroxy)-ceramide. Six mammalian ceramide synthase/longevity assurance homologue (CerS/LASS) family members...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-11-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520346137 |