Nicotinamide phosphoribosyltransferase: Biology, role in cancer, and novel drug target
The nicotinamide adenine dinucleotide (NAD+) pool is an important electron exchanger in tumor biology. The salvage pathway plays an important role in the regulation of the levels of cellular NAD+ biosynthesis and the nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme of this...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2018-01-01
|
Series: | Cancer Translational Medicine |
Subjects: | |
Online Access: | http://www.cancertm.com/article.asp?issn=2395-3977;year=2018;volume=4;issue=4;spage=109;epage=116;aulast=Lucena-Cacace |