Effects of combination therapy indacaterol/glycopyrronium versus tiotropium on moderate to severe COPD: evaluation of impulse oscillometry and exacerbation rate

Abstract Background Small airways are considered the major site of airflow limitation in COPD. Impulse oscillometry (IOS) is a forced oscillation technique, which provides passive measurement of lung mechanics. It can differentiate small airway from large airway obstruction and is more sensitive tha...

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Bibliographic Details
Main Authors: Antonio Molino, Francesca Simioli, Anna Agnese Stanziola, Mauro Mormile, Maria Martino, Maria D’Amato
Format: Article
Language:English
Published: PAGEPress Publications 2017-09-01
Series:Multidisciplinary Respiratory Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40248-017-0105-4