Effects of combination therapy indacaterol/glycopyrronium versus tiotropium on moderate to severe COPD: evaluation of impulse oscillometry and exacerbation rate
Abstract Background Small airways are considered the major site of airflow limitation in COPD. Impulse oscillometry (IOS) is a forced oscillation technique, which provides passive measurement of lung mechanics. It can differentiate small airway from large airway obstruction and is more sensitive tha...
Main Authors: | Antonio Molino, Francesca Simioli, Anna Agnese Stanziola, Mauro Mormile, Maria Martino, Maria D’Amato |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2017-09-01
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Series: | Multidisciplinary Respiratory Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40248-017-0105-4 |
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