Evaluation of antinociceptive profile of chalcone derivative (3-(2,5-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one (DMPF-1) in vivo

Evaluation of antinociceptive profile of chalcone derivative (3-(2,5-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one (DMPF-1) in vivo

Introduction: Pain is a major global health issue, where its pharmacotherapy prompts unwanted side effects; hence, the development of effective alternative compounds from natural derivatives with lesser side effects is clinically needed. Chalcone; the precursors of flavonoid, and its derivatives hav...

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Bibliographic Details
Main Authors: Noor Azlina Abu Bakar, Mohd Roslan Sulaiman, Nordin Lajis, Mohd Nadeem Akhtar, Azam Shah Mohamad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
3-(2
-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one
abdominal writhing
antinociceptive
chalcone
glutamatergic
hot plate
opioidergic
transient protein vanilloid-1
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2020;volume=12;issue=6;spage=711;epage=717;aulast=Abu

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http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2020;volume=12;issue=6;spage=711;epage=717;aulast=Abu

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