Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primates.

Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primates.

Plasmodium vivax malaria causes significant morbidity and mortality worldwide, and only one drug is in clinical use that can kill the hypnozoites that cause P. vivax relapses. HIV and P. vivax malaria geographically overlap in many areas of the world, including South America and Asia. Despite the in...

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Bibliographic Details
Main Authors: Charlotte V Hobbs, Saurabh Dixit, Scott R Penzak, Tejram Sahu, Sachy Orr-Gonzalez, Lynn Lambert, Katie Zeleski, Jingyang Chen, Jillian Neal, William Borkowsky, Yimin Wu, Patrick E Duffy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4277318?pdf=render

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http://europepmc.org/articles/PMC4277318?pdf=render

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