A synthetic cell-penetrating peptide derived from nuclear localization signal of EPS8 exerts anticancer activity against acute myeloid leukemia

A synthetic cell-penetrating peptide derived from nuclear localization signal of EPS8 exerts anticancer activity against acute myeloid leukemia

Abstract Background Oncogenic roles of epidermal growth factor receptor pathway substrate no.8 (EPS8) have been widely reported in various tumors, making targeting of EPS8 an appealing prospect. Here, we describe the role of EPS8 in acute myeloid leukemia (AML) and consider the potential of EPS8 as...

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Bibliographic Details
Main Authors: Yiran Chen, Xiaoling Xie, Anqin Wu, Lei Wang, Yuxing Hu, Honghao Zhang, Yuhua Li
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Epidermal growth factor receptor pathway substrate no.8 (EPS8)
Acute myeloid leukemia
Peptide
Nuclear localization signal
Online Access:http://link.springer.com/article/10.1186/s13046-018-0682-x

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http://link.springer.com/article/10.1186/s13046-018-0682-x

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