Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine

Despite the success of current vaccination against poliomyelitis, safe, cheap and effective vaccines remain sought for continuing eradication effort. Here the authors use plants to express stabilized virus-like particles of type 3 poliovirus that can induce a protective immune response in mice trans...

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Bibliographic Details
Main Authors: Johanna Marsian, Helen Fox, Mohammad W. Bahar, Abhay Kotecha, Elizabeth E. Fry, David I. Stuart, Andrew J. Macadam, David J. Rowlands, George P. Lomonossoff
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00090-w