Disruption of CTNND2, encoding delta-catenin, causes a penetrant attention deficit disorder and myopia

Disruption of CTNND2, encoding delta-catenin, causes a penetrant attention deficit disorder and myopia

Attention deficit hyperactivity disorder (ADHD) is a common and highly heritable neurodevelopmental disorder with poorly understood pathophysiology and genetic mechanisms. A balanced chromosomal translocation interrupts CTNND2 in several members of a family with profound attentional deficit and myop...

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Bibliographic Details
Main Authors: Abidemi Adegbola, Richard Lutz, Elina Nikkola, Samuel P. Strom, Jonathan Picker, Anthony Wynshaw-Boris
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:HGG Advances
Subjects:
attention deficit hyperactivity disorder (ADHD)
translocation mapping
whole genome sequencing
Nanopore sequencing
familial ADHD
refractive error of the eye
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247720300075

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http://www.sciencedirect.com/science/article/pii/S2666247720300075

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