Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with poor survival. Age is a major risk factor, and both alveolar epithelial cells and lung fibroblasts in this disease exhibit features of cellular senescence, a hallmark of ageing. Accumulation of fibrotic extracellular matrix (ECM)...
Main Authors: | Kaj E. C. Blokland, Habibie Habibie, Theo Borghuis, Greta J. Teitsma, Michael Schuliga, Barbro N. Melgert, Darryl A. Knight, Corry-Anke Brandsma, Simon D. Pouwels, Janette K. Burgess |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/7/1628 |
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