Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia

Treating premature infants with high oxygen is a routine intervention in the context of neonatal intensive care. Unfortunately, the increase in survival rates is associated with various detrimental sequalae of hyperoxia exposure, most notably bronchopulmonary dysplasia (BPD), a disease of disrupted...

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Bibliographic Details
Main Authors: Monica Reis, Gareth R. Willis, Angeles Fernandez-Gonzalez, Vincent Yeung, Elizabeth Taglauer, Margaret Magaletta, Teagan Parsons, Alan Derr, Xianlan Liu, Rene Maehr, Stella Kourembanas, S. Alex Mitsialis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
mesechymal stromal cell
extracellular vesicle (EV)
neonatal immune system
hyperoxia (oxygen)
thymus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.640595/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.640595/full

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