Factors that influence response classifications in chemotherapy treated patient-derived xenografts (PDX)

In this study, we investigated the impact of initial tumor volume, rate of tumor growth, cohort size, study duration, and data analysis method on chemotherapy treatment response classifications in patient-derived xenografts (PDXs). The analyses were conducted on cisplatin treatment response data for...

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Bibliographic Details
Main Authors: Joan E. Malcolm, Timothy M. Stearns, Susan D. Airhart, Joel H. Graber, Carol J. Bult
Format: Article
Language:English
Published: PeerJ Inc. 2019-03-01
Series:PeerJ
Subjects:
PDX
Online Access:https://peerj.com/articles/6586.pdf