Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis

Monitoring changes in immune phenotype during the progression of multiple sclerosis can provide insight into disease progression and inform treatment. Here the authors develop engineered biomaterial-based immunological niches for easy access to innate immune cells in a mouse model of multiple sclero...

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Bibliographic Details
Main Authors: Aaron H. Morris, Kevin R. Hughes, Robert S. Oakes, Michelle M. Cai, Stephen D. Miller, David N. Irani, Lonnie D. Shea
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17629-z