The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain
Neuropathic pain results from neuroplasticity in nociceptive neuronal networks. Here we demonstrate that control of alternative pre-mRNA splicing, through the splice factor serine-arginine splice factor 1 (SRSF1), is integral to the processing of nociceptive information in the spinal cord.Neuropathi...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-12-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996116302261 |