Exploring Protein–Protein Interaction in the Study of Hormone-Dependent Cancers

Exploring Protein–Protein Interaction in the Study of Hormone-Dependent Cancers

Estrogen receptors promote target gene transcription when they form a dimer, in which two identical (homodimer) or different (heterodimer) proteins are bound to each other. In hormone-dependent cancers, hormone receptor dimerization plays pivotal roles, not only in the pathogenesis or development of...

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Bibliographic Details
Main Authors: Yasuhiro Miki, Erina Iwabuchi, Katsuhiko Ono, Hironobu Sasano, Kiyoshi Ito
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
protein–protein interaction
co-immunoprecipitation
bioluminescence resonance energy transfer/förster resonance energy transfer
immunohistochemistry
in situ proximity ligation assay
super-resolution microscopy
estrogen receptor
Online Access:http://www.mdpi.com/1422-0067/19/10/3173

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http://www.mdpi.com/1422-0067/19/10/3173

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