Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

Modulating natural killer cell functions in human immunity and reproduction are diverse interactions between the killer cell immunoglobulin-like receptors (KIR) of Natural Killer (NK) cells and HLA class I ligands on the surface of tissue cells. Dominant interactions are between KIR2DL1 and the C2 e...

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Bibliographic Details
Main Authors: Hugo G Hilton, Paul J Norman, Neda Nemat-Gorgani, Ana Goyos, Jill A Hollenbach, Brenna M Henn, Christopher R Gignoux, Lisbeth A Guethlein, Peter Parham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4546388?pdf=render

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http://europepmc.org/articles/PMC4546388?pdf=render

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