Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy

Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy

Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare, inheritable cardiac disorder characterized by ventricular tachyarrhythmias, progressive loss of cardiomyocytes with fibrofatty replacement and sudden cardiac death. The exact underlying mechanisms are unclear. Methods: Thi...

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Bibliographic Details
Main Authors: Fanis Buljubasic, Ibrahim El-Battrawy, Huan Lan, Santosh K. Lomada, Anupriya Chatterjee, Zhihan Zhao, Xin Li, Rujia Zhong, Qiang Xu, Mengying Huang, Zhenxing Liao, Siegfried Lang, Lukas Cyganek, Xiaobo Zhou, Thomas Wieland, Martin Borggrefe, Ibrahim Akin
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Journal of Clinical Medicine
Subjects:
arrhythmogenic right ventricular cardiomyopathy
human-induced pluripotent stem cell-derived cardiomyocyte
nucleoside diphosphate kinase
sk4 channel
arrhythmia
Online Access:https://www.mdpi.com/2077-0383/9/2/486

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https://www.mdpi.com/2077-0383/9/2/486

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