Diffuse microvascular C5b-9 deposition is a common feature in muscle and nerve biopsies from diabetic patients

Diffuse microvascular C5b-9 deposition is a common feature in muscle and nerve biopsies from diabetic patients

Abstract Terminal complement complex deposition in endomysial capillaries detected by a C5b-9 immunostain is considered a diagnostic feature for dermatomyositis. However, we found widespread microvascular C5b-9 reactivity in a substantial subset of muscle biopsies with denervation changes, and in ne...

Full description

Bibliographic Details
Main Authors: Paul C. Yell, Dennis K. Burns, Evan G. Dittmar, Charles L. White, Chunyu Cai
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Acta Neuropathologica Communications
Subjects:
Peripheral neuropathy
C5b-9
Terminal complement complex
Diabetes
Nerve biopsy
Muscle biopsy
Online Access:http://link.springer.com/article/10.1186/s40478-018-0512-6

Internet

http://link.springer.com/article/10.1186/s40478-018-0512-6

Similar Items