Parenteral artemisinins are associated with reduced mortality and neurologic deficits and improved long-term behavioral outcomes in children with severe malaria

Parenteral artemisinins are associated with reduced mortality and neurologic deficits and improved long-term behavioral outcomes in children with severe malaria

Abstract Background In 2011, the World Health Organization recommended injectable artesunate as the first-line therapy for severe malaria (SM) due to its superiority in reducing mortality compared to quinine. There are limited data on long-term clinical and neurobehavioral outcomes after artemisinin...

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Bibliographic Details
Main Authors: Andrea L. Conroy, Robert O. Opoka, Paul Bangirana, Ruth Namazzi, Allen E. Okullo, Michael K. Georgieff, Sarah Cusick, Richard Idro, John M. Ssenkusu, Chandy C. John
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Medicine
Subjects:
Artemisinin
Artesunate
Quinine
Mortality
Severe malaria
Neurologic deficit
Online Access:https://doi.org/10.1186/s12916-021-02033-1

Internet

https://doi.org/10.1186/s12916-021-02033-1

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